Intensive Management of Chronic Bronchorrhea in a Tracheostomized Duchenne Patient with Bronchiectasis

Duchenne muscular dystrophy (DMD) is a severe neuromuscular (NM) disease, considered as the most common and rapidly evolutive muscular dystrophy. The incidence of this X-linked hereditary disease is approximately 1/3000 [1] to 3500 [2] male births. DMD is caused by mutation of the dystrophin gene which leads to the absence of dystrophin in muscle tissue [1] Missing dystrophin precludes normal muscle contraction and leads to progressive muscle weakness. Muscle weakness typically leads to functional tetraplegia, the need for mechanical ventilation and techniques of airway clearance, and ultimately death.